The initiation, propagation and dynamics of CRISPR-SpyCas9 R-loop complex

CRISPR-Cas9 system has been widely used for efficient genome editing. Although the structures of Cas9 protein in complex with single-guided RNA (sgRNA) and target DNA have been resolved, the molecular details about the formation of Cas9 endonuclease R-loop structure remain elusive. Here we examine t...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Zeng, Yan, Cui, Yang, Zhang, Yong, Zhang, Yanruo, Liang, Meng, Chen, Hui, Lan, Jie, Song, Guangtao, Lou, Jizhong
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
RNA and RNA-protein complexes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758904/
https://ncbi.nlm.nih.gov/pubmed/29145633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1117
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky