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How does Sec63 affect the conformation of Sec61 in yeast?

The Sec complex catalyzes the translocation of proteins of the secretory pathway into the endoplasmic reticulum and the integration of membrane proteins into the endoplasmic reticulum membrane. Some substrate peptides require the presence and involvement of accessory proteins such as Sec63. Recently...

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Publicat a:PLoS Comput Biol
Autors principals: Bhadra, Pratiti, Yadhanapudi, Lalitha, Römisch, Karin, Helms, Volkhard
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8031780/
https://ncbi.nlm.nih.gov/pubmed/33780447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008855
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