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The Sec63p J-Domain Is Required for ERAD of Soluble Proteins in Yeast

How misfolded proteins are exported from the ER to the cytosol for degradation (ER-associated Degradation, ERAD) and which proteins are participating in this process is not understood. Several studies using a single, leaky mutant indicated that Sec63p might be involved in ERAD. More recently, Sec63p...

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Detalhes bibliográficos
Main Authors: Servas, Christina, Römisch, Karin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852996/
https://ncbi.nlm.nih.gov/pubmed/24324744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082058
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