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How does Sec63 affect the conformation of Sec61 in yeast?

The Sec complex catalyzes the translocation of proteins of the secretory pathway into the endoplasmic reticulum and the integration of membrane proteins into the endoplasmic reticulum membrane. Some substrate peptides require the presence and involvement of accessory proteins such as Sec63. Recently...

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Publicado en:PLoS Comput Biol
Autores principales: Bhadra, Pratiti, Yadhanapudi, Lalitha, Römisch, Karin, Helms, Volkhard
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8031780/
https://ncbi.nlm.nih.gov/pubmed/33780447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008855
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