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ERAD and protein import defects in a sec61 mutant lacking ER-lumenal loop 7
BACKGROUND: The Sec61 channel mediates protein translocation across the endoplasmic reticulum (ER) membrane during secretory protein biogenesis, and likely also during export of misfolded proteins for ER-associated degradation (ERAD). The mechanisms of channel opening for the different modes of tran...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3897919/ https://ncbi.nlm.nih.gov/pubmed/24314051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-14-56 |
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