Quantification of von Willebrand factor and ADAMTS-13 after traumatic injury: a pilot study

BACKGROUND: Von Willebrand factor (VWF) is an acute phase reactant synthesized in the megakaryocytes and endothelial cells. VWF forms ultra-large multimers (ULVWF) which are cleaved by the metalloprotease ADAMTS-13, preventing spontaneous VWF–platelet interaction. After trauma, ULVWF is released int...

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Bibliographic Details
Published in:Trauma Surg Acute Care Open
Main Authors: MacArthur, Taleen A, Goswami, Julie, Moon Tasson, Laurie, Tischer, Alexander, Bailey, Kent R, Spears, Grant M, Dong, Jing-Fei, Auton, Matthew, Kozar, Rosemary, Park, Myung S
Format: Artigo
Language:Inglês
Published: BMJ Publishing Group 2021
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8030476/
https://ncbi.nlm.nih.gov/pubmed/33912688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/tsaco-2021-000703
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