A Multi-Omics Analysis of Metastatic Melanoma Identifies a Germinal Center-Like Tumor Microenvironment in HLA-DR-Positive Tumor Areas

The emergence of immune checkpoint inhibitors has dramatically changed the therapeutic landscape for patients with advanced melanoma. However, relatively low response rates and a high incidence of severe immune-related adverse events have prompted the search for predictive biomarkers. A positive pre...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Front Oncol
Main Authors: Gadeyne, Laura, Van Herck, Yannick, Milli, Giorgia, Atak, Zeynep Kalender, Bolognesi, Maddalena Maria, Wouters, Jasper, Marcelis, Lukas, Minia, Angeliki, Pliaka, Vaia, Roznac, Jan, Alexopoulos, Leonidas G., Cattoretti, Giorgio, Bechter, Oliver, Oord, Joost Van Den, De Smet, Frederik, Antoranz, Asier, Bosisio, Francesca Maria
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2021
נושאים:
Oncology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029980/
https://ncbi.nlm.nih.gov/pubmed/33842341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.636057
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