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Solid stress-induced migration is mediated by GDF15 through Akt pathway activation in pancreatic cancer cells

Solid stress is a biomechanical abnormality of the tumor microenvironment that plays a crucial role in tumor progression. When it is applied to cancer cells, solid stress hinders their proliferation rate and promotes cancer cell invasion and metastatic potential. However, the underlying mechanisms o...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Kalli, Maria, Minia, Angeliki, Pliaka, Vaia, Fotis, Christos, Alexopoulos, Leonidas G., Stylianopoulos, Triantafyllos
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6353927/
https://ncbi.nlm.nih.gov/pubmed/30700740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37425-6
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