A Multi-Omics Analysis of Metastatic Melanoma Identifies a Germinal Center-Like Tumor Microenvironment in HLA-DR-Positive Tumor Areas

The emergence of immune checkpoint inhibitors has dramatically changed the therapeutic landscape for patients with advanced melanoma. However, relatively low response rates and a high incidence of severe immune-related adverse events have prompted the search for predictive biomarkers. A positive pre...

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Bibliografski detalji
Izdano u:Front Oncol
Glavni autori: Gadeyne, Laura, Van Herck, Yannick, Milli, Giorgia, Atak, Zeynep Kalender, Bolognesi, Maddalena Maria, Wouters, Jasper, Marcelis, Lukas, Minia, Angeliki, Pliaka, Vaia, Roznac, Jan, Alexopoulos, Leonidas G., Cattoretti, Giorgio, Bechter, Oliver, Oord, Joost Van Den, De Smet, Frederik, Antoranz, Asier, Bosisio, Francesca Maria
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Oncology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029980/
https://ncbi.nlm.nih.gov/pubmed/33842341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.636057
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