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MAP2 Splicing is Altered in Huntington's Disease

Dendritic alteration of striatal medium spiny neurons is one of the earliest morphological abnormalities in Huntington's disease (HD). The main microtubule‐associated protein in dendrites is MAP2. The low‐molecular weight isoforms of MAP2 (LMW‐MAP2) are the juvenile forms resulting from exclusi...

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Bibliographic Details
Published in:Brain Pathol
Main Authors: Cabrera, Jorge Rubén, Lucas, José J.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029395/
https://ncbi.nlm.nih.gov/pubmed/27098187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12387
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