Modeling the C9ORF72 repeat expansion mutation using human induced pluripotent stem cells

C9ORF72 repeat expansion is the most frequent causal genetic mutation giving rise to amyotrophic lateral sclerosis (ALS) and fronto‐temporal dementia (FTD). The relatively recent discovery of the C9ORF72 repeat expansion in 2011 and the complexity of the mutation have meant that animal models that s...

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Detaylı Bibliyografya
Yayımlandı:Brain Pathol
Asıl Yazarlar: Selvaraj, Bhuvaneish T., Livesey, Matthew R., Chandran, Siddharthan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2017
Konular:
MINI‐SYMPOSIUM: USING iPSCs TO UNDERSTAND HUMAN NEUROLOGICAL DISEASE: POTENTIAL AND LIMITATIONS
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029270/
https://ncbi.nlm.nih.gov/pubmed/28585384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12520
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