Early Pharmacotherapy with Fluoxetine Rescues Dendritic Pathology in the Ts65Dn Mouse Model of Down Syndrome

Down syndrome DS is a genetic pathology characterized by brain hypotrophy and severe cognitive impairment. Although defective neurogenesis is an important determinant of mental disability, a severe dendritic pathology appears to be an equally important factor. A previous study showed that fluoxetine...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Brain Pathol
Autori principali: Guidi, Sandra, Stagni, Fiorenza, Bianchi, Patrizia, Ciani, Elisabetta, Ragazzi, Elena, Trazzi, Stefania, Grossi, Gabriele, Mangano, Chiara, Calzà, Laura, Bartesaghi, Renata
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2012
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8028975/
https://ncbi.nlm.nih.gov/pubmed/22817700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2012.00624.x
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