The sterol regulatory element‐binding protein 2 is dysregulated by tau alterations in Alzheimer disease

Disturbed neuronal cholesterol homeostasis has been observed in Alzheimer disease (AD) and contributes to the pathogenesis of AD. As the master switch of cholesterol biosynthesis, the sterol regulatory element‐binding protein 2 (SREBP‐2) translocates to the nucleus after cleavage/activation, but its...

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Dades bibliogràfiques
Publicat a:Brain Pathol
Autors principals: Wang, Chunyu, Zhao, Fanpeng, Shen, Katie, Wang, Wenzhang, Siedlak, Sandra L., Lee, Hyoung‐gon, Phelix, Clyde F., Perry, George, Shen, Lu, Tang, Beisha, Yan, Riqiang, Zhu, Xiongwei
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8028548/
https://ncbi.nlm.nih.gov/pubmed/30515907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12691
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