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Estrogen receptor-α is localized to neurofibrillary tangles in Alzheimer’s disease

The female predominance for developing Alzheimer disease (AD) suggests the involvement of gender specific factor(s) such as a reduced estrogen-estrogen receptor signaling in the pathogenesis of AD. The potential role of ERα in AD pathogenesis has been explored by several groups with mixed results. W...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Chunyu, Zhang, Fan, Jiang, Sirui, Siedlak, Sandra L., Shen, Lu, Perry, George, Wang, Xinglong, Tang, Beisha, Zhu, Xiongwei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4738266/
https://ncbi.nlm.nih.gov/pubmed/26837465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20352
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