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Posttranslational modifications of α-tubulin in alzheimer disease
BACKGROUND: In Alzheimer disease (AD), hyperphosphorylation of tau proteins results in microtubule destabilization and cytoskeletal abnormalities. Our prior ultra-morphometric studies documented a clear reduction in microtubules in pyramidal neurons in AD compared to controls, however, this reductio...
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| Publicado no: | Transl Neurodegener |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4448339/ https://ncbi.nlm.nih.gov/pubmed/26029362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-015-0030-4 |
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