RIP1 kinase activity promotes steatohepatitis through mediating cell death and inflammation in macrophages

Hepatocyte cell death and liver inflammation have been well recognized as central characteristics of nonalcoholic steatohepatitis (NASH), however, the underlying molecular basis remains elusive. The kinase receptor-interacting protein 1 (RIP1) is a multitasking molecule with distinct functions in re...

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Pubblicato in:Cell Death Differ
Autori principali: Tao, Liang, Yi, Yuguo, Chen, Yuxin, Zhang, Haibing, Orning, Pontus, Lien, Egil, Jie, Jiapeng, Zhang, Weigao, Xu, Qian, Li, Yang, Ding, Zhao, Wu, Chao, Ding, Qiurong, Wang, Junsong, Zhang, Jianfa, Weng, Dan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027792/
https://ncbi.nlm.nih.gov/pubmed/33208891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00668-w
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