TGR5 Regulates Macrophage Inflammation in Nonalcoholic Steatohepatitis by Modulating NLRP3 Inflammasome Activation

Nonalcoholic steatohepatitis (NASH) is a chronic liver disease associated with dysregulation of liver metabolism and inflammation. G-protein coupled bile acid receptor 1 (TGR5) is a cell surface receptor that is involved in multiple metabolic pathways. However, the functions of TGR5 in regulating ma...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Shi, Yong, Su, Wantong, Zhang, Lei, Shi, Chengyu, Zhou, Jinren, Wang, Peng, Wang, Hao, Shi, Xiaoli, Wei, Song, Wang, Qi, Auwerx, Johan, Schoonjans, Kristina, Yu, Yue, Pan, Rui, Zhou, Haoming, Lu, Ling
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7937818/
https://ncbi.nlm.nih.gov/pubmed/33692776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.609060
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