RIP1 kinase activity promotes steatohepatitis through mediating cell death and inflammation in macrophages

Hepatocyte cell death and liver inflammation have been well recognized as central characteristics of nonalcoholic steatohepatitis (NASH), however, the underlying molecular basis remains elusive. The kinase receptor-interacting protein 1 (RIP1) is a multitasking molecule with distinct functions in re...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Tao, Liang, Yi, Yuguo, Chen, Yuxin, Zhang, Haibing, Orning, Pontus, Lien, Egil, Jie, Jiapeng, Zhang, Weigao, Xu, Qian, Li, Yang, Ding, Zhao, Wu, Chao, Ding, Qiurong, Wang, Junsong, Zhang, Jianfa, Weng, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027792/
https://ncbi.nlm.nih.gov/pubmed/33208891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00668-w
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