LW-213 induces cell apoptosis in human cutaneous T-cell lymphomas by activating PERK–eIF2α–ATF4–CHOP axis

Cutaneous T-cell lymphoma (CTCL) is characterized by a heterogeneous group of extranodal non-Hodgkin lymphomas, in which monoclonal T lymphocytes infiltrate the skin. LW-213, a derivative of wogonin, was found to induce cell apoptosis in chronic myeloid leukemia (CML). In this study, we investigated...

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Publicat a:Acta Pharmacol Sin
Autors principals: Yu, Xiao-xuan, Zhu, Meng-yuan, Wang, Jia-rong, Li, Hui, Hu, Po, Qing, Ying-jie, Wang, Xiang-yuan, Wang, Hong-zheng, Wang, Zhan-yu, Xu, Jing-yan, Guo, Qing-long, Hui, Hui
Format: Artigo
Idioma:Inglês
Publicat: Springer Singapore 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027432/
https://ncbi.nlm.nih.gov/pubmed/32747719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-020-0466-7
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