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Emerging Role for the PERK/eIF2α/ATF4 in Human Cutaneous Leishmaniasis
Leishmania parasites utilize adaptive evasion mechanisms in infected macrophages to overcome host defenses and proliferate. We report here that the PERK/eIF2α/ATF4 signaling branch of the integrated endoplasmic reticulum stress response (IERSR) is activated by Leishmania and this pathway is importan...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5719050/ https://ncbi.nlm.nih.gov/pubmed/29213084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17252-x |
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