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Increasing hepatic glycogen moderates the diabetic phenotype in insulin-deficient Akita mice

Hepatic glycogen metabolism is impaired in diabetes. We previously demonstrated that strategies to increase liver glycogen content in a high-fat-diet mouse model of obesity and insulin resistance led to a reduction in food intake and ameliorated obesity and glucose tolerance. These effects were acco...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: López-Soldado, Iliana, Guinovart, Joan J., Duran, Jordi
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027280/
https://ncbi.nlm.nih.gov/pubmed/33667544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100498
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