Deleterious effects of neuronal accumulation of glycogen in flies and mice

Under physiological conditions, most neurons keep glycogen synthase (GS) in an inactive form and do not show detectable levels of glycogen. Nevertheless, aberrant glycogen accumulation in neurons is a hallmark of patients suffering from Lafora disease or other polyglucosan disorders. Although these...

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Detalhes bibliográficos
Main Authors: Duran, Jordi, Tevy, María Florencia, Garcia-Rocha, Mar, Calbó, Joaquim, Milán, Marco, Guinovart, Joan J
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494072/
https://ncbi.nlm.nih.gov/pubmed/22549942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201200241
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