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Deleterious effects of neuronal accumulation of glycogen in flies and mice

Under physiological conditions, most neurons keep glycogen synthase (GS) in an inactive form and do not show detectable levels of glycogen. Nevertheless, aberrant glycogen accumulation in neurons is a hallmark of patients suffering from Lafora disease or other polyglucosan disorders. Although these...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Duran, Jordi, Tevy, María Florencia, Garcia-Rocha, Mar, Calbó, Joaquim, Milán, Marco, Guinovart, Joan J
Format: Artigo
Langue:Inglês
Publié: WILEY-VCH Verlag 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494072/
https://ncbi.nlm.nih.gov/pubmed/22549942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201200241
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