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Lack of Neuronal Glycogen Impairs Memory Formation and Learning-Dependent Synaptic Plasticity in Mice

Since brain glycogen is stored mainly in astrocytes, the role of this polysaccharide in neurons has been largely overlooked. To study the existence and relevance of an active neuronal glycogen metabolism in vivo, we generated a mouse model lacking glycogen synthase specifically in the Camk2a-express...

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Détails bibliographiques
Publié dans:Front Cell Neurosci
Auteurs principaux: Duran, Jordi, Gruart, Agnès, Varea, Olga, López-Soldado, Iliana, Delgado-García, José M., Guinovart, Joan J.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700221/
https://ncbi.nlm.nih.gov/pubmed/31456667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00374
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