Lack of Neuronal Glycogen Impairs Memory Formation and Learning-Dependent Synaptic Plasticity in Mice

Since brain glycogen is stored mainly in astrocytes, the role of this polysaccharide in neurons has been largely overlooked. To study the existence and relevance of an active neuronal glycogen metabolism in vivo, we generated a mouse model lacking glycogen synthase specifically in the Camk2a-express...

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Veröffentlicht in:Front Cell Neurosci
Hauptverfasser: Duran, Jordi, Gruart, Agnès, Varea, Olga, López-Soldado, Iliana, Delgado-García, José M., Guinovart, Joan J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700221/
https://ncbi.nlm.nih.gov/pubmed/31456667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00374
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