Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) Interacts With Colony-Stimulating Factor 1 Receptor (CSF1R) but Is Not Necessary for CSF1/CSF1R-Mediated Microglial Survival

Triggering receptor expressed on myeloid cells-2 (TREM2) and colony-stimulating factor 1 receptor (CSF1R) are crucial molecules for microgliopathy, which is characterized by microglia dysfunction and has recently been proposed as the neuropathological hallmark of neurological disorders. TREM2 and CS...

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Pubblicato in:Front Immunol
Autori principali: Cheng, Baoying, Li, Xin, Dai, Kai, Duan, Shengshun, Rong, Zhouyi, Chen, Yingmin, Lü, Liangcheng, Liu, Zhaoji, Huang, Xiaohua, Xu, Huaxi, Zhang, Yun-Wu, Zheng, Honghua
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027073/
https://ncbi.nlm.nih.gov/pubmed/33841415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.633796
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