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Elevated EZH2 in Ischemic Heart Disease Epigenetically Mediates Suppression of Na(V)1.5 Expression

Suppression of the cardiac sodium channel Na(V)1.5 leads to fatal arrhythmias in ischemic heart disease (IHD). However, the transcriptional regulation of Na(V)1.5 in cardiac ischemia is still unclear. Our studies are aimed to investigate the expression of enhancer of zeste homolog 2 (EZH2) in IHD an...

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Bibliografski detalji
Izdano u:J Mol Cell Cardiol
Glavni autori: Zhao, Limei, You, Tao, Lu, Yan, Lin, Shin, Li, Faqian, Xu, Haodong
Format: Artigo
Jezik:Inglês
Izdano: 2020
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026576/
https://ncbi.nlm.nih.gov/pubmed/33370552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2020.12.012
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