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Elevated EZH2 in Ischemic Heart Disease Epigenetically Mediates Suppression of Na(V)1.5 Expression

Suppression of the cardiac sodium channel Na(V)1.5 leads to fatal arrhythmias in ischemic heart disease (IHD). However, the transcriptional regulation of Na(V)1.5 in cardiac ischemia is still unclear. Our studies are aimed to investigate the expression of enhancer of zeste homolog 2 (EZH2) in IHD an...

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Detalhes bibliográficos
Publicado no:J Mol Cell Cardiol
Main Authors: Zhao, Limei, You, Tao, Lu, Yan, Lin, Shin, Li, Faqian, Xu, Haodong
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026576/
https://ncbi.nlm.nih.gov/pubmed/33370552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2020.12.012
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