Protocol for measurement of calcium dysregulation in human induced pluripotent stem cell-derived dopaminergic neurons

Calcium regulation is a critical process in neurons, and Ca(2+) signaling is a major contributor to neurological disorders including Parkinson’s disease (PD). Here, combining calcium imaging with whole-cell Ca(2+) current recording, we provide a detailed protocol for measuring Ca(2+) homeostasis in...

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Bibliographische Detailangaben
Veröffentlicht in:STAR Protoc
Hauptverfasser: Yin, Xiling, Kim, Jungwoo Wren, Liu, Shiyu, Dawson, Ted M., Dawson, Valina L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2021
Schlagworte:
Protocol
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024766/
https://ncbi.nlm.nih.gov/pubmed/33855307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2021.100405
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