Neurons Derived from Human Induced Pluripotent Stem Cells Integrate into Rat Brain Circuits and Maintain Both Excitatory and Inhibitory Synaptic Activities

The human cerebral cortex is a complex structure with tightly interconnected excitatory and inhibitory neuronal networks. In order to study human cortical function, we recently developed a method to generate cortical neurons from human induced pluripotent stem cells (hiPSCs) that form both excitator...

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Bibliografische gegevens
Gepubliceerd in:eNeuro
Hoofdauteurs: Yin, Xiling, Xu, Jin-Chong, Cho, Gun-sik, Kwon, Chulan, Dawson, Ted M., Dawson, Valina L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2019
Onderwerpen:
New Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6709226/
https://ncbi.nlm.nih.gov/pubmed/31413152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0148-19.2019
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