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Cultured networks of excitatory projection neurons and inhibitory interneurons for studying human cortical neurotoxicity

Translating neuroprotective treatments from discovery in cell and animal models to the clinic has proven challenging. To reduce the gap between basic studies of neurotoxicity and neuroprotection and clinically relevant therapies, we developed a human cortical neuron culture system from human embryon...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Xu, Jin-Chong, Fan, Jing, Wang, Xueqing, Eacker, Stephen M., Kam, Tae-In, Chen, Li, Yin, Xiling, Zhu, Juehua, Chi, Zhikai, Jiang, Haisong, Chen, Rong, Dawson, Ted M., Dawson, Valina L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595216/
https://ncbi.nlm.nih.gov/pubmed/27053772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aad0623
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