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Targeting SLP76:ITK interaction separates GVHD from GVL in allo-HSCT
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative therapy for hematological malignancies, due to graft-versus-leukemia (GVL) activity mediated by alloreactive donor T cells. However, graft-versus-host disease (GVHD) is also mediated by these cells. Here, we assessed the ef...
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| 出版年: | iScience |
|---|---|
| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8024657/ https://ncbi.nlm.nih.gov/pubmed/33851101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102286 |
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