Lgals3bp suppresses colon inflammation and tumorigenesis through the downregulation of TAK1-NF-κB signaling

Galectin 3-binding protein (LGALS3BP, also known as 90K) is a multifunctional glycoprotein involved in immunity and cancer. However, its precise role in colon inflammation and tumorigenesis remains unclear. Here, we showed that Lgals3bp(−/−) mice were highly susceptible to colitis and colon tumorige...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Cell Death Discov
Huvudupphovsmän: Cho, Sang-Hee, Shim, Hyun-Jeong, Park, Mi-Ra, Choi, Ji-Na, Akanda, Md Rashedunnabi, Hwang, Jun-Eul, Bae, Woo-Kyun, Lee, Kyung-Hwa, Sun, Eun-Gene, Chung, Ik-Joo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2021
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024364/
https://ncbi.nlm.nih.gov/pubmed/33824294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-021-00447-7
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk