Lgals3bp suppresses colon inflammation and tumorigenesis through the downregulation of TAK1-NF-κB signaling

Galectin 3-binding protein (LGALS3BP, also known as 90K) is a multifunctional glycoprotein involved in immunity and cancer. However, its precise role in colon inflammation and tumorigenesis remains unclear. Here, we showed that Lgals3bp(−/−) mice were highly susceptible to colitis and colon tumorige...

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Detalhes bibliográficos
Publicado no:Cell Death Discov
Main Authors: Cho, Sang-Hee, Shim, Hyun-Jeong, Park, Mi-Ra, Choi, Ji-Na, Akanda, Md Rashedunnabi, Hwang, Jun-Eul, Bae, Woo-Kyun, Lee, Kyung-Hwa, Sun, Eun-Gene, Chung, Ik-Joo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024364/
https://ncbi.nlm.nih.gov/pubmed/33824294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-021-00447-7
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