Lipocalin 2 mediates appetite suppression during pancreatic cancer cachexia

Lipocalin 2 (LCN2) was recently identified as an endogenous ligand of the type 4 melanocortin receptor (MC4R), a critical regulator of appetite. However, it remains unknown if this molecule influences appetite during cancer cachexia, a devastating clinical entity characterized by decreased nutrition...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Olson, Brennan, Zhu, Xinxia, Norgard, Mason A., Levasseur, Peter R., Butler, John T., Buenafe, Abigail, Burfeind, Kevin G., Michaelis, Katherine A., Pelz, Katherine R., Mendez, Heike, Edwards, Jared, Krasnow, Stephanie M., Grossberg, Aaron J., Marks, Daniel L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024334/
https://ncbi.nlm.nih.gov/pubmed/33824339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22361-3
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