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DNA with zwitterionic and negatively charged phosphate modifications: Formation of DNA triplexes, duplexes and cell uptake studies

Two phosphate modifications were introduced into the DNA backbone using the Staudinger reaction between the 3’,5’-dinucleoside β-cyanoethyl phosphite triester formed during DNA synthesis and sulfonyl azides, 4-(azidosulfonyl)-N,N,N-trimethylbutan-1-aminium iodide (N+ azide) or p-toluenesulfonyl (tos...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Su, Yongdong, Bayarjargal, Maitsetseg, Hale, Tracy K, Filichev, Vyacheslav V
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8022206/
https://ncbi.nlm.nih.gov/pubmed/33828619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.17.65
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