Targeting duplex DNA with chimeric α,β-triplex-forming oligonucleotides

Triplex-directed DNA recognition is strictly limited by polypurine sequences. In an attempt to address this problem with synthetic biology tools, we designed a panel of short chimeric α,β-triplex-forming oligonucleotides (TFOs) and studied their interaction with fluorescently labelled duplex hairpin...

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Bibliographic Details
Main Authors: Kolganova, N. A., Shchyolkina, A. K., Chudinov, A. V., Zasedatelev, A. S., Florentiev, V. L., Timofeev, E. N.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
Subjects:
Synthetic Biology and Chemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439883/
https://ncbi.nlm.nih.gov/pubmed/22641847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks410
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