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Targeting duplex DNA with chimeric α,β-triplex-forming oligonucleotides
Triplex-directed DNA recognition is strictly limited by polypurine sequences. In an attempt to address this problem with synthetic biology tools, we designed a panel of short chimeric α,β-triplex-forming oligonucleotides (TFOs) and studied their interaction with fluorescently labelled duplex hairpin...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3439883/ https://ncbi.nlm.nih.gov/pubmed/22641847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks410 |
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