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Microarray Detection of Duplex and Triplex DNA Binders with DNA-Modified Gold Nanoparticles

We have designed a chip-based assay, using microarray technology, for determining the relative binding affinities of duplex and triplex DNA binders. This assay combines the high discrimination capabilities afforded by DNA-modified Au nanoparticles with the high-throughput capabilities of DNA microar...

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Autors principals: Lytton-Jean, Abigail K. R., Han, Min Su, Mirkin, Chad A.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525617/
https://ncbi.nlm.nih.gov/pubmed/17614366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac070635h
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