Nicotinamide Mononucleotide Attenuates Renal Interstitial Fibrosis After AKI by Suppressing Tubular DNA Damage and Senescence

Acute kidney injury (AKI) is a worldwide health problem currently lacking therapeutics that directly promote renal repair or prevent the occurrence of chronic fibrosis. DNA damage is a feature of many forms of kidney injury, and targeting DNA damage and repair might be effective strategies for kidne...

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Bibliographische Detailangaben
Veröffentlicht in:Front Physiol
Hauptverfasser: Jia, Yan, Kang, Xin, Tan, Lishan, Ren, Yifei, Qu, Lei, Tang, Jiawei, Liu, Gang, Wang, Suxia, Xiong, Zuying, Yang, Li
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Physiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8021789/
https://ncbi.nlm.nih.gov/pubmed/33833691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.649547
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