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Nicotinamide Supplementation Attenuates Renal Interstitial Fibrosis via Boosting the Activity of Sirtuins

BACKGROUND: Progressive tubulointerstitial fibrosis (TIF) is the final common pathway leading to ESRD. There is an urgent need to develop effective approaches slowing the progression of TIF. Previous studies showed that systemic supplementation of nicotinamide (NAM) increases renal NAD<sup>+&l...

詳細記述

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書誌詳細
出版年:Kidney Dis (Basel)
主要な著者: Zhen, Xin, Zhang, Shaowu, Xie, Feifei, Zhou, Miaomiao, Hu, Zheng, Zhu, Fengxin, Nie, Jing
フォーマット: Artigo
言語:Inglês
出版事項: S. Karger AG 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8216029/
https://ncbi.nlm.nih.gov/pubmed/34179114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000510943
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