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HSP72 attenuates renal tubular cell apoptosis and interstitial fibrosis in obstructive nephropathy

Although heat shock protein 72 kDa (HSP72) protects tubular epithelium from a variety of acute insults, its role in chronic renal injury and fibrosis is poorly characterized. In this study, we tested the hypothesis that HSP72 reduces apoptosis and epithelial-to-mesenchymal transition (EMT), importan...

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Detalhes bibliográficos
Main Authors: Mao, Haiping, Li, Zhilian, Zhou, Yi, Li, Zhijian, Zhuang, Shougang, An, Xin, Zhang, Baiyu, Chen, Wei, Nie, Jing, Wang, Zhiyong, Borkan, Steven C., Wang, Yihan, Yu, Xueqing
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116425/
https://ncbi.nlm.nih.gov/pubmed/18417540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00468.2007
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