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Nicotinamide mononucleotide attenuates glucocorticoid-induced osteogenic inhibition by regulating the SIRT1/PGC-1α signaling pathway

Long-term and high-dose glucocorticoid treatment is recognized as an important influencing factor for osteoporosis and osteonecrosis. Nicotinamide mononucleotide (NMN) is an intermediate of NAD(+) biosynthesis, and is widely used to replenish the levels of NAD(+). However, the potential role of NMN...

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Publicat a:Mol Med Rep
Autors principals: Huang, Rui-Xiong, Tao, Jun
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7248519/
https://ncbi.nlm.nih.gov/pubmed/32377728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11116
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