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PDLIM2 repression by ROS in alveolar macrophages promotes lung tumorigenesis
One of the most fundamental and challenging questions in the field of cancer is how immunity is transformed from tumor immunosurveillance to tumor-promoting inflammation. Here, we identified the tumor suppressor PDZ-LIM domain–containing protein 2 (PDLIM2) as a checkpoint of alveolar macrophages (AM...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | JCI Insight |
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| Κύριοι συγγραφείς: | , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Clinical Investigation
2021
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8021114/ https://ncbi.nlm.nih.gov/pubmed/33539325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.144394 |
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