Role of Electrostatic Hotspots in the Selectivity of Complement Control Proteins Toward Human and Bovine Complement Inhibition

Poxviruses are dangerous pathogens, which can cause fatal infection in unvaccinated individuals. The causative agent of smallpox in humans, variola virus, is closely related to the bovine vaccinia virus, yet the molecular basis of their selectivity is currently incompletely understood. Here, we exam...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Narkhede, Yogesh B., Gautam, Avneesh K., Hsu, Rohaine V., Rodriguez, Wilson, Zewde, Nehemiah T., Harrison, Reed E. S., Arantes, Pablo R., Gaieb, Zied, Gorham, Ronald D., Kieslich, Chris, Morikis, Dimitrios, Sahu, Arvind, Palermo, Giulia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Molecular Biosciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020814/
https://ncbi.nlm.nih.gov/pubmed/33829039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.618068
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