The CysLT(2)R receptor mediates leukotriene C(4)-driven acute and chronic itch

Acute and chronic itch are burdensome manifestations of skin pathologies including allergic skin diseases and atopic dermatitis, but the underlying molecular mechanisms are not well understood. Cysteinyl leukotrienes (CysLTs), comprising LTC(4), LTD(4), and LTE(4), are produced by immune cells durin...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Voisin, Tiphaine, Perner, Caroline, Messou, Marie-Angele, Shiers, Stephanie, Ualiyeva, Saltanat, Kanaoka, Yoshihide, Price, Theodore J., Sokol, Caroline L., Bankova, Lora G., Austen, K. Frank, Chiu, Isaac M.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2021
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020753/
https://ncbi.nlm.nih.gov/pubmed/33753496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2022087118
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