The CysLT(2)R receptor mediates leukotriene C(4)-driven acute and chronic itch

Acute and chronic itch are burdensome manifestations of skin pathologies including allergic skin diseases and atopic dermatitis, but the underlying molecular mechanisms are not well understood. Cysteinyl leukotrienes (CysLTs), comprising LTC(4), LTD(4), and LTE(4), are produced by immune cells durin...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Voisin, Tiphaine, Perner, Caroline, Messou, Marie-Angele, Shiers, Stephanie, Ualiyeva, Saltanat, Kanaoka, Yoshihide, Price, Theodore J., Sokol, Caroline L., Bankova, Lora G., Austen, K. Frank, Chiu, Isaac M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020753/
https://ncbi.nlm.nih.gov/pubmed/33753496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2022087118
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