The CysLT(2)R receptor mediates leukotriene C(4)-driven acute and chronic itch

Acute and chronic itch are burdensome manifestations of skin pathologies including allergic skin diseases and atopic dermatitis, but the underlying molecular mechanisms are not well understood. Cysteinyl leukotrienes (CysLTs), comprising LTC(4), LTD(4), and LTE(4), are produced by immune cells durin...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Voisin, Tiphaine, Perner, Caroline, Messou, Marie-Angele, Shiers, Stephanie, Ualiyeva, Saltanat, Kanaoka, Yoshihide, Price, Theodore J., Sokol, Caroline L., Bankova, Lora G., Austen, K. Frank, Chiu, Isaac M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2021
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020753/
https://ncbi.nlm.nih.gov/pubmed/33753496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2022087118
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