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Naturally Occurring Point Mutation Cys460Trp Located in the I-EGF1 Domain of Integrin β3 Alters the Binding of Some anti-HPA-1a Antibodies
BACKGROUND: Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is caused by the destruction of platelets in the fetus or newborn by maternal platelet alloantibodies (Abs), mostly against human platelet antigen (HPA)-1a. Recent studies indicate that two anti-HPA-subtypes exist: type I reacts with...
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| Publicat a: | Transfusion |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8020566/ https://ncbi.nlm.nih.gov/pubmed/32770549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/trf.15960 |
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