Naturally Occurring Point Mutation Cys460Trp Located in the I-EGF1 Domain of Integrin β3 Alters the Binding of Some anti-HPA-1a Antibodies

BACKGROUND: Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is caused by the destruction of platelets in the fetus or newborn by maternal platelet alloantibodies (Abs), mostly against human platelet antigen (HPA)-1a. Recent studies indicate that two anti-HPA-subtypes exist: type I reacts with...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Transfusion
Hlavní autoři: Holzwarth, Sarah Theresa, Bayat, Behnaz, Zhu, Jieqing, Phuangtham, Roongaroon, Fischer, Lars, Boeckelmann, Doris, Roeder, Lida, Berghöfer, Heike, Schmidt, Silke, Bein, Gregor, Santoso, Sentot
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020566/
https://ncbi.nlm.nih.gov/pubmed/32770549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/trf.15960
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky