Loading...
Reduction BACE1 expression via suppressing NF-κB mediated signaling by Tamibarotene in a mouse model of Alzheimer’s disease
This present study examined the effect of Tamibarotene (AM80) in APP/PS1 mice, a well-established AD mouse model. AM80 was intraperitoneal administered to 3-month-old APP/PS1 mice at a dose of 5 mg/kg/day for 16 weeks. The results clearly showed that AM80 could reduce amyloid-β peptides through impa...
Saved in:
| Published in: | IBRO Neurosci Rep |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Elsevier
2021
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8019995/ https://ncbi.nlm.nih.gov/pubmed/33842919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ibneur.2021.02.004 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|