BET inhibitor suppresses melanoma progression via the noncanonical NF-κB/SPP1 pathway

Background: Bromodomain and extra-terminal domain (BET) inhibitors have shown profound efficacy against hematologic malignancies and solid tumors in preclinical studies. However, the underlying molecular mechanism in melanoma is not well understood. Here we identified secreted phosphoprotein 1 (SPP1...

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Dettagli Bibliografici
Pubblicato in:Theranostics
Autori principali: Deng, Guangtong, Zeng, Furong, Su, Juan, Zhao, Shuang, Hu, Rui, Zhu, Wu, Hu, Shuo, Chen, Xiang, Yin, Mingzhu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2020
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7546000/
https://ncbi.nlm.nih.gov/pubmed/33052224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.47432
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